Key result
In nonischemic dilated cardiomyopathy, atrial fibrillation was associated with significantly lower hyperemic myocardial perfusion compared to sinus rhythm (1.32 vs 2.52 mL/min/mL; P=0.022).
Why the study?
Is persistent atrial fibrillation associated with impaired myocardial perfusion in patients with nonischemic dilated cardiomyopathy?
Observational (n=52)
Is persistent atrial fibrillation associated with impaired myocardial perfusion in patients with nonischemic dilated cardiomyopathy?
Absolute Event Rate: 1.32% vs 2.52%
p-value: p=0.022
In patients with nonischemic dilated cardiomyopathy, the presence of persistent atrial fibrillation is associated with significantly reduced myocardial perfusion reserve and increased coronary resistance compared to those in sinus rhythm.
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Hypothesis-generating for perfusion impairment in AF with NIDCM; prospective studies needed before any clinical implications.
Range et al. (2009) conducted an observational in Nonischemic Dilated Cardiomyopathy (n=52). Atrial fibrillation vs. Sinus rhythm was evaluated on Hyperemic myocardial perfusion (p=0.022). In nonischemic dilated cardiomyopathy, atrial fibrillation was associated with significantly lower hyperemic myocardial perfusion compared to sinus rhythm (1.32 vs 2.52 mL/min/mL; P=0.022).
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