Globally in 2019, there were 3,331,144 incident cases, 219,437 deaths, and 6,579,978 DALYs due to atrial fibrillation in older adults aged 60-89 years, with high BMI and high systolic blood pressure as predominant risk factors.
Observational
The global burden of atrial fibrillation in older adults remains high and is increasing in lower sociodemographic index regions, driven significantly by high BMI and systolic blood pressure.
Background: Atrial fibrill ation (AF) is a predominant public health concern in older adults. Therefore, this study aimed to explore the global, regional, and national burden of AF in older adults aged 60-89 between 1990 and 2019. Methods: The morbidity, mortality, disability-adjusted life years (DALYs), and age-standardized rates of AF were refined from the Global Burden of Diseases study 2019. The epidemiological characteristics were assessed based on numerical values, age-standardized rates per 100,000 person-years, and estimated annual percentage changes (EAPC). Results: Globally, a total of 33.31 million AF cases, 219.4 thousand deaths, and 65.80 million DALYs were documented in 2019. There were no appreciable changes in EAPC from 1990 to 2019. The disease burden of AF differed significantly across different territories and countries. At the national level, China exhibited the highest number of incident cases 818,493 (562,871-1,128,695), deaths 39,970 (33,722-46,387), and DALYs 1,383,674 (1,047,540-1,802,516). At the global level, high body mass index (BMI) and high systolic blood pressure (SBP) were two predominant risk factors contributing to the proportion of AF-related deaths. Conclusion: AF in older adults remains a major public health concern worldwide. The burden of AF varies widely at both national and regional levels. From 1990 to 2019, the cases of incidences, deaths, and DALYs have shown a global increase. The ASIR, ASMR, and ASDR have declined in the high-moderate and high SDI regions; however, the burden of AF increased promptly in the lower SDI regions. Special attention should be paid to the main risk factors for high-risk individuals with AF, which can help control systolic blood pressure and body mass index within normal limits. Over all, it is necessary to illustrate the features of the global AF burden and develop more effective and targeted prevention and treatment strategies.
Jiao et al. (Mon,) conducted a observational in Atrial fibrillation. Globally in 2019, there were 3,331,144 incident cases, 219,437 deaths, and 6,579,978 DALYs due to atrial fibrillation in older adults aged 60-89 years, with high BMI and high systolic blood pressure as predominant risk factors.