Key result
Recent clinical trials demonstrate that orally active β-blockers can reduce the risk of cardiovascular mortality in patients recovering from acute myocardial infarction.
Why the study?
Do orally active β-blockers reduce cardiovascular mortality in patients recovering from acute myocardial infarction?
Do orally active β-blockers reduce cardiovascular mortality in patients recovering from acute myocardial infarction?
Orally active β-blockers are effective in reducing cardiovascular mortality in survivors of acute myocardial infarction.
Affirms β-blocker use post-MI; confirms trial benefits but leaves open optimal duration in reperfusion era.
THE β-adrenoceptor antagonists have been shown to be both safe and effective for the treatment of systemic hypertension, arrhythmia, angina pectoris, hypertrophic cardiomyopathy, thyrotoxicosis, and open-angle glaucoma, and for prophylaxis against migraine headache.1 Recent clinical trials with one to four years of active treatment have demonstrated that some orally active β-blockers can reduce the risk of cardiovascular mortality in patients recovering from acute myocardial infarction.2 3 4 5 6 7 8 9 10 11 12 13 14 15 On the basis of the results of the Norwegian Multicenter Study10 and the Beta-Blocker Heart Attack Trial11 in North America, the Food and Drug Administration has recently approved two nonselective β-blockers, timolol maleate (Blocadren) and . . .
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Koch‐Weser et al. (1984) conducted a review in Acute Myocardial Infarction. β-Adrenergic Blockade was evaluated. Recent clinical trials demonstrate that orally active β-blockers can reduce the risk of cardiovascular mortality in patients recovering from acute myocardial infarction.
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