Key result
Normal neonatal LV dimensions increase linearly from birth to 28 days to establish age-based nomograms.
Why the study?
Previous studies on neonatal cardiac dimensions in Africa were cross-sectional and evaluated mainly children with very few newborns.
Cohort (n=120)
Yes
This study provides normal echocardiographic nomograms for left ventricular dimensions in healthy term Nigerian neonates over their first 28 days of life.
May aid LV echo interpretation in Nigerian neonates; extends normative data but requires validation before wider use.
Background: Previous studies on neonatal cardiac dimensions in Africa were cross-sectional, evaluating mainly children with very few newborns. This study was carried out in a cohort of normal newborns with normal maternal cardiotocograms, systemic finding, and pulse oximetry at birth.Materials and Methods: One-hundred and twenty term normal newborns were recruited from March 2015 to December 2015 from the Adeoyo Maternity Teaching Hospital and the University College Hospital, Ibadan, Oyo State, Southwest Nigeria. The mothers were monitored during labor using cardiotocography 7 fetal/maternal monitor to ensure that the baby suffered no perinatal stress. Pulse oximetry was also done at birth. Left ventricular dimension in diastole, left ventricular posterior wall thickness in diastole, left ventricular dimension in systole, and left ventricular posterior wall thickness in systole and aortic dimension were measured at birth and weekly till 28 days using M-mode according to American Society of Echocardiography.Results: All mothers recruited had spontaneous vaginal delivery with normal cardiotocographic measurements. Appearance, pulse, grimace, activity, and respiration scores ranged between 7–8 at 1 min and 8–10 at 5 min. There were 60 (50%) males and 60 (50%) females. All of the left ventricular measurements showed a linear increase in their values with age. Nomograms have been plotted based on age using 95% confidence interval.Conclusion: This study has shed some light on the possibility of deriving normal values of echocardiographic dimensions for this age group and derived nomogram. This has added to the already existing data on the nomograms of the newborn, especially in the Nigerian Newborn.
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Omokhodion et al. (2019) conducted a cohort in Normal term neonates (n=120). Echocardiographic measurements was evaluated on Left ventricular dimensions and nomograms. Left ventricular echocardiographic measurements in normal term neonates showed a linear increase with age from birth to 28 days, allowing for the derivation of age-based nomograms.
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