Key result
Congenital long QT syndrome is an inherited disorder of cardiac repolarization that can be classified by genetic mutations and triggers, and should be suspected based on ECG or family history.
Provides an overview of congenital long QT syndrome, including its presentation, triggers, and genetic classification, tailored for primary care physicians.
May improve primary care detection of congenital long QT syndrome; leaves open validation of trigger-based genetic classification.
Congenital long QT syndrome is an inherited disorder of cardiac repolarization that predisposes to syncope and to sudden death from polymorphic ventricular tachycardia. The disorder should be suspected when the electrocardiogram shows characteristic QT abnormalities, or when there is a family history of long QT syndrome or of an event that raises suspicion of long QT syndrome, such as sudden death, syncope, or ill-defined "seizure" disorder. We can now classify some types of congenital long QT syndrome according to their genetic mutations and their triggers, such as exercise, rest, or startle.
No takes yet. Share an insight, caveat, or question.
Levine et al. (2008) conducted a review in Congenital long QT syndrome. Congenital long QT syndrome is an inherited disorder of cardiac repolarization that can be classified by genetic mutations and triggers, and should be suspected based on ECG or family history.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: