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February 23, 2016Journal of the American Heart AssociationOpen Access

Hospital and 4‐Year Mortality Predictors in Patients With Acute Pulmonary Edema With and Without Coronary Artery Disease

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Key result

CAD in acute pulmonary edema is linked to ~23% higher overall mortality.

  • P=0.002
  • n=806

Population

806 consecutive patients with acute pulmonary edema admitted from 2000 to 2010, stratified by the presence…

Design

Cohort

Follow-up

45 months (range 10-140)

Authors

JFJaume FiguerasJBJordi BañerasCPCarlos Peña

Discussion

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Overview

CAD identifies higher-risk acute pulmonary edema patients; leaves open whether intensified management improves outcomes.

Study Design

Type

Cohort (n=806)

Structured PICO

P
Population
806 consecutive patients with acute pulmonary edema (APE) admitted from 2000 to 2010, stratified by the presence (n=638) or absence (n=168) of coronary artery disease (CAD).
O
Outcome
Hospital mortality and long-term overall mortalityhard clinical

Main Result

Absolute Event Rate: 70% vs 57.1%

p-value: p=0.002

In patients with acute pulmonary edema, the presence of coronary artery disease is associated with higher long-term mortality and heart failure readmissions, highlighting a high-risk population that may benefit from aggressive intervention.

Cite This Study

Figueras et al. (2016) conducted a cohort in Acute Pulmonary Edema (n=806). Coronary artery disease vs. No coronary artery disease was evaluated on Overall mortality (p=0.002). Acute pulmonary edema patients with coronary artery disease had higher overall mortality over a 45-month follow-up than those without coronary artery disease (70.0% vs 57.1%; P=0.002).

synapsesocial.com/papers/6a0f777c2badbc352afe35dahttps://doi.org/10.1161/jaha.115.002581
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Also Consider

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  1. 1Acute Pulmonary Oedema: Clinical Characteristics, Prognostic Factors, and in-Hospital Management2010 · 53 citations
  2. 2Prognostic Factors in Acute Pulmonary Edema1986 · 85 citations
  3. 3The Development of a Simple Risk Score to Predict Early Outcome in Severe Acute Acidotic Cardiogenic Pulmonary Edema2009 · 10 citations
  4. 4Characteristics, outcomes, and predictors of 1-year mortality in patients hospitalized for acute heart failure2006 · 228 citations
  5. 5Acute Heart Failure: Clinical Presentation, One-Year Mortality and Prognostic Factors2005 · 176 citations