Key result
Biatrial high-density contact mapping revealed that complex fractionated atrial electrogram areas are located in close proximity (median 5 mm) to high dominant frequency sites during atrial fibrillation.
Observational (n=20)
Effect estimate: r = -0.50
p-value: p=0.03
Complex fractionated atrial electrograms and high dominant frequency sites are spatially adjacent rather than perfectly overlapping during atrial fibrillation, suggesting a mechanistic relationship.
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Does not yet support CFAE- or DF-guided ablation in AF; extends mechanistic understanding of arrhythmia maintenance.
Stiles et al. (2008) conducted an observational in Atrial fibrillation (n=20). Biatrial high-density contact mapping was evaluated on Correlation between complex fractionated atrial electrograms (CFAE) and dominant frequency (DF) (r = -0.50, p=0.03). Biatrial high-density contact mapping revealed that complex fractionated atrial electrogram areas are located in close proximity (median 5 mm) to high dominant frequency sites during atrial fibrillation.