January 4, 2012Circulation Arrhythmia and Electrophysiology

Functional Nature of Electrogram Fractionation Demonstrated by Left Atrial High-Density Mapping

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Population

18 patients undergoing high-density, 3-dimensional, left-atrial mapping

Design

Cross-sectional

Authors

AJAmir JadidiElectrophysiology EDEdward DuncanUniversity of Stirling SMShinsuke MiyazakiElectrophysiology

Discussion

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Implication

Questions reliability of continuous CFAE as fixed ablation targets; supports functional, activation-dependent nature of fractionation.

Structured PICO

Population

18 patients (9 with persistent atrial fibrillation) undergoing high-density, 3-dimensional, left-atrial mapping

Intervention

High-density, 3-dimensional, left-atrial mapping (>400 points/map) during atrial fibrillation (AF), sinus rhythm (SR), and coronary sinus-paced (CSp) rhythms

Outcome

Anatomic distribution and correlation of complex fractionated atrial electrograms (CFAE) sites between different rhythmssurrogate

Fractionated electrograms in the left atrium are highly variable and functional in nature, depending on the direction and rate of activation rather than representing fixed structural scar.

Cite This Study

Jadidi et al. (2012) studied this question.

synapsesocial.com/papers/6a7ec903c4fd4e6484339564 https://doi.org/10.1161/circep.111.964197

Topics

Atrial fibrillation Persistent AF management AF ablation outcomes

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Functional Nature of Electrogram Fractionation Demonstrated by Left Atrial High-Density Mapping

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Topics

Functional Nature of Electrogram Fractionation Demonstrated by Left Atrial High-Density Mapping

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Topics

Also Consider