Key result
Transition to chronic atrial fibrillation occurred in 33.1% of patients with paroxysmal atrial fibrillation and was associated with a several-fold higher incidence of embolic complications.
Why the study?
What is the incidence and timing of embolic complications in patients with paroxysmal atrial fibrillation?
Population
426 patients with initial paroxysmal atrial fibrillation (PAF)
Design
Cohort
Authors
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May identify high-risk windows for embolism during AF progression; leaves open whether anticoagulation timing should be adjusted.
Cohort (n=426)
What is the incidence and timing of embolic complications in patients with paroxysmal atrial fibrillation?
Embolic events cluster at the onset of paroxysmal AF and shortly after transition to chronic AF, highlighting critical periods where anticoagulation may be most beneficial.
Petersen et al. (1986) conducted a cohort in Paroxysmal atrial fibrillation (n=426). Transition to chronic atrial fibrillation (CAF) vs. Paroxysmal atrial fibrillation (PAF) was evaluated on Embolic complications. Transition to chronic atrial fibrillation occurred in 33.1% of patients with paroxysmal atrial fibrillation and was associated with a several-fold higher incidence of embolic complications.
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