Persons dying instantaneously of coronary artery disease differed from those dying suddenly, with >50% dying during or after exertion and frequently exhibiting old occluded coronary arteries.
Observational (n=59)
What are the clinical and pathological differences between instantaneous and sudden death in patients with coronary artery disease?
Instantaneous death in coronary artery disease is often associated with physical exertion, primary arrhythmia, and specific chronic coronary occlusions without acute lesions, suggesting potential for angiographic risk stratification.
A study of 59 persons dying of coronary artery disease revealed that persons dying instantaneously differed from persons dying suddenly of coronary artery disease in that (1) they rarely experienced acute symptoms or exhibited acute signs before death; (2) more than one half died during or immediately after physical exertion; (3) their deaths appeared to result from a primary arrhythmia; and (4) their hearts rarely showed an acute lesion of any kind and frequently exhibited two old occluded coronary arteries or one old occluded, left anterior descending artery. These latter differences should permit angiographic detection of many persons prone to instantaneous death.
Meyer Friedman (Mon,) conducted a observational in Coronary artery disease (n=59). Instantaneous death vs. Sudden death was evaluated on Clinical and pathological differences between instantaneous and sudden death. Persons dying instantaneously of coronary artery disease differed from those dying suddenly, with >50% dying during or after exertion and frequently exhibiting old occluded coronary arteries.