Key result
Methodological recommendations for assessing quality of life in heart failure emphasize using conventional scoring methods, analyzing dimensions separately, and evaluating survival independently.
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Provides methodological recommendations for assessing symptoms and quality of life in heart failure trials.
Scoring * Use conventional methods * Keep weightings simple or avoid if possible * Analyse sensitivity Multidimensional issues * Specify key variables before starting study * Analyse each dimension separately * Test for treatment-dimension interactions Withdrawal of patients * All subjects should complete quality of life assessments at withdrawal *Analyse quality of life and survival separately Clinically inportant effects
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Coats et al. (1994) conducted a review in Heart failure. Methodological recommendations for assessing quality of life in heart failure emphasize using conventional scoring methods, analyzing dimensions separately, and evaluating survival independently.
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