Methodological recommendations for assessing quality of life in heart failure emphasize using conventional scoring methods, analyzing dimensions separately, and evaluating survival independently.
Provides methodological recommendations for assessing symptoms and quality of life in heart failure trials.
Scoring * Use conventional methods * Keep weightings simple or avoid if possible * Analyse sensitivity Multidimensional issues * Specify key variables before starting study * Analyse each dimension separately * Test for treatment-dimension interactions Withdrawal of patients * All subjects should complete quality of life assessments at withdrawal *Analyse quality of life and survival separately Clinically inportant effects
Coats et al. (1994) conducted a review in Heart failure. Methodological recommendations for assessing quality of life in heart failure emphasize using conventional scoring methods, analyzing dimensions separately, and evaluating survival independently.