Key result
Supervised cardiac rehab in pediatric and CHD patients carries a low ~4% nonsustained VT risk.
Why the study?
Cardiac rehabilitation is underused in pediatric and congenital heart disease populations, where concern about arrhythmia risk may be an obstacle to referral.
Does a standardized cardiac rehabilitation program increase the risk of clinically significant arrhythmias in pediatric and congenital heart disease patients?
Cohort (n=177)
No
Does a standardized cardiac rehabilitation program increase the risk of clinically significant arrhythmias in pediatric and congenital heart disease patients?
Supervised cardiac rehabilitation in pediatric and congenital heart disease patients is safe and associated with a low risk of clinically significant arrhythmias.
Answers are grounded in this paper and cite their sources.
Supports supervised cardiac rehabilitation feasibility in this population; leaves open need for randomized confirmation of arrhythmia safety.
BACKGROUND: Cardiac rehabilitation (CR) is underused in pediatric and congenital heart disease populations. Concern about arrhythmia risk may be an obstacle to CR referral. We sought to describe the frequency and risk factors for arrhythmia in patients who participated in a standardized CR program. METHODS: We conducted a retrospective chart review of all patients who completed at least 1 CR encounter from 2017 to 2022 at a pediatric cardiology center. We used descriptive statistics to determine the frequency of atrial and ventricular ectopy. Logistic regression was performed to identify predictors of frequent ventricular ectopy, nonsustained ventricular tachycardia, or ventricular tachycardia. RESULTS: There were 177 patients who participated in 4494 rehabilitation encounters over the 6-year study period (median age, 17 years [14-22]). Most patients had congenital heart disease (63%). Moderate or severe systolic dysfunction was noted in 14% of patients. Presence of an implantable cardioverter-defibrillator (9% of patients) and a ventricular assist device (5% of patients) was noted. Nonsustained ventricular tachycardia occurred in 7 patients (3.9%) across 18 sessions (0.4%). There was an episode of sustained ventricular tachycardia resulting in an appropriate implantable cardioverter-defibrillator shock. There were no deaths. Patients ≥18 years old (odds ratio, 2.7 [95% CI, 1.1 - 6.4]) were more likely to have frequent ventricular ectopy, nonsustained ventricular tachycardia, or ventricular tachycardia. CONCLUSIONS: Supervised CR in pediatric and congenital heart disease populations is associated with a low risk for clinically significant arrhythmias, and should not be an obstacle to referral for individuals who would otherwise benefit from CR.
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Warren et al. (2025) conducted a cohort in Pediatric and congenital heart disease (n=177). Cardiac rehabilitation was evaluated on Frequency of atrial and ventricular ectopy and predictors of frequent ventricular ectopy, nonsustained ventricular tachycardia, or ventricular tachycardia (OR 2.7, 95% CI 1.1 - 6.4). Supervised cardiac rehabilitation in pediatric and congenital heart disease patients had a low arrhythmia risk, with nonsustained ventricular tachycardia occurring in 3.9% of patients.
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