Key result
AF driver ablation boosts odds of freedom from AF ~3-fold versus controls.
Why the study?
Does ablation of AF drivers in addition to PVI or as a stand-alone procedure improve freedom from AF and all arrhythmias in patients with atrial fibrillation?
Meta-Analysis (n=3,294)
Does ablation of AF drivers in addition to PVI or as a stand-alone procedure improve freedom from AF and all arrhythmias in patients with atrial fibrillation?
Effect estimate: OR 3.1 (95% CI 1.3-7.7)
p-value: p=0.02
The addition of AF driver ablation to PVI may improve single-procedure freedom from arrhythmias, though current evidence is limited by study heterogeneity and a lack of randomized controlled trials.
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AF driver ablation may boost single-procedure AF freedom with PVI; leaves open confirmation by dedicated RCTs amid heterogeneity.
Baykaner et al. (2018) conducted a meta-analysis in atrial fibrillation (n=3,294). AF driver ablation vs. controls was evaluated on freedom from AF (OR 3.1, 95% CI 1.3-7.7, p=0.02). AF driver ablation added to PVI or as a stand-alone procedure significantly improved freedom from AF compared with controls (OR 3.1; 95% CI 1.3-7.7; P=0.02).
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