Key result
Anhedonia shows greater prevalence than depressed mood in older adults, increasing from age 70.
Cross-Sectional (n=2,861)
No
In older adults, anhedonia is more prevalent than depressed mood and increases after age 70, suggesting that depression treatment may benefit from individualized profiling of these symptoms.
Anhedonia may warrant distinct assessment in adults ≥70; cross-sectional data leaves open causal links and targeted interventions.
Precision medicine approaches to depression argue for the assessment of individual client profiles of the two major diagnostic criteria of depressed mood and anhedonia. To explore this suggestion, 1,513 males and 1,348 females aged between 55 and 87 years from Newcastle, Australia, completed the Center for Epidemiological Studies-Depression Scale (CESD). Total CESD score and the two sets of scores gradually increased with age; females had significantly higher scores on total CESD and the two subsets of scores. Anhedonia showed greater prevalence than depressed mood and also increased from age 70 years, whereas depressed mood remained fairly stable until age 80 years. Treatment efficacy for depression may benefit from consideration of individual client profiles on these two aspects of depression.
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Sharpley et al. (2016) conducted a cross-sectional in Depression (n=2,861). Anhedonia showed greater prevalence than depressed mood and increased from age 70 years, whereas depressed mood remained fairly stable until age 80 years among 2,861 older adults.
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