Key result
Atrial fibrillation ablation in patients <45 years achieved similar AF control (87%) compared to older age groups (82-88%, P=0.06), with no major complications and higher freedom from AF off drugs.
Why the study?
Does catheter ablation for atrial fibrillation in patients <45 years of age improve AF control and reduce complications compared to older patients?
Cohort (n=1,548)
Does catheter ablation for atrial fibrillation in patients <45 years of age improve AF control and reduce complications compared to older patients?
p-value: p=0.06
Catheter ablation for atrial fibrillation in patients under 45 is highly safe and effective, with a greater likelihood of maintaining sinus rhythm without antiarrhythmic drugs compared to older patients, supporting its consideration as first-line therapy.
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Supports ablation consideration in young AF patients; extends observational data but leaves open first-line role pending RCTs.
Leong‐Sit et al. (2010) conducted a cohort in Atrial Fibrillation (n=1,548). Atrial fibrillation ablation vs. Older age groups (≥45 years) was evaluated on AF control (no or rare AF on or off antiarrhythmic drugs) (p=0.06). Atrial fibrillation ablation in patients <45 years achieved similar AF control (87%) compared to older age groups (82-88%, P=0.06), with no major complications and higher freedom from AF off drugs.
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