Key result
Platelets drive critical processes beyond thrombosis including inflammation, wound healing, angiogenesis, and tumor metastasis.
This review highlights the multifaceted roles of platelets extending beyond hemostasis to include immunity, thrombosis, and interactions in cancer and infections.
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May inform antiplatelet strategies in cancer and infection; extends prior knowledge but remains hypothesis-generating pending trials.
Filho et al. (2017) conducted a review in Platelet biology and function. Platelets play crucial roles beyond hemostasis and thrombosis, actively participating in wound healing, inflammation, antimicrobial host defense, angiogenesis, and tumor metastasis.
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