Key result
Two EV71 vaccines gain approval in China as multiple candidates advance to late-stage trials.
Why the study?
What is the current status of research and development of vaccines against enterovirus 71?
Population
Children, especially younger than 3 years old, susceptible to enterovirus 71 (EV71) infection
Design
Review
Authors
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Chinese EV71 approvals advance prevention options; leaves open global efficacy and rollout data.
What is the current status of research and development of vaccines against enterovirus 71?
This review highlights the progress in EV71 vaccine development, noting recent approvals in China, which could significantly impact the prevention of severe HFMD complications in young children.
Reed et al. (2016) conducted a review in Hand, Foot, and Mouth Disease (HFMD) / enterovirus 71 (EV71) infection. EV71 vaccines was evaluated. Several EV71 vaccine candidates have progressed to late-stage clinical trials in the Asia-Pacific region, with two vaccines recently approved by regulatory authorities in China.
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