Key result
Resting elite athletes show ~9% troponin I elevation, suggesting troponin T is a more reliable marker.
Why the study?
Strenuous physical activity can cause transient, typically benign increases in troponin levels, but troponin I and T release independent of competition-related physical stress required evaluation in elite athletes.
Does the release of troponin I differ from troponin T in high-performance athletes outside of competition?
Cross-Sectional (n=219)
Does the release of troponin I differ from troponin T in high-performance athletes outside of competition?
Troponin T may be a more reliable indicator than troponin I for ruling out cardiac damage in high-performance athletes, as troponin I is frequently elevated as a benign response to intense physical training.
May warrant preferring troponin T in athlete cardiac evaluations; hypothesis-generating and leaves open prospective validation.
Troponin I and troponin T are critical biomarkers for myocardial infarction and damage and are pivotal in cardiological and laboratory diagnostics, including emergency settings. Rapid testing protocols have been developed for urgent care, particularly in emergency outpatient clinics. Studies indicate that strenuous physical activity can cause transient increases in these troponin levels, which are typically considered benign. This research focused on 219 elite athletes from national teams, evaluating their troponin I and T levels as part of routine sports medical exams, independent of competition-related physical stress. The results showed that 9.2% (18 athletes) had elevated troponin I levels above the reporting threshold, while their troponin T levels remained within the normal range. Conversely, only 0.9% (two athletes) had normal troponin I but raised troponin T levels, and 2.3% (five athletes) exhibited increases in both markers. No significant cardiovascular differences were noted between those with elevated troponin levels and those without. This study concludes that elevated troponin I is a common response to the intense physical training endured by high-performance endurance athletes, whereas troponin T elevation does not seem to be directly linked to physical exertion in this group. For cardiac assessments, particularly when ruling out cardiac damage in these athletes, troponin T might be a more reliable indicator than troponin I.
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Wuestenfeld et al. (2024) conducted a cross-sectional in High-performance athletes (n=219). Measurement of Troponin I and Troponin T was evaluated on Elevated troponin I and troponin T levels above the reporting threshold. Routine evaluation of 219 elite athletes outside of competition revealed elevated troponin I in 9.2% and isolated troponin T elevation in 0.9%, suggesting troponin T is a more reliable cardiac marker.
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