Exercise intensity and duration significantly affect postexercise cardiac troponin elevation, which is usually physiological but may rarely unmask subclinical cardiac disease.
How do age, sex, sport type, exercise intensity, duration, and training level influence the postexercise release of cardiac troponin?
Postexercise cardiac troponin elevation is generally a physiological response driven by exercise intensity and duration, though further research is needed to define normal ranges across diverse demographics.
BACKGROUND: Postexercise release of cardiac troponin (cTn) is a well-known phenomenon, although the influence of various confounders remains unclear. The aim of this critical review was to analyze the postexercise release of cTn according to age, sex, different types of sport, exercise intensity and duration, and training level. DATA SOURCES: A literature search was performed within the National Library of Medicine using the following keywords: cTn, peak, release, and exercise. The search was further refined by adding the keywords athletes, children/adolescents, and sport. MAIN RESULTS: For final analysis, 52 studies were included: 43 adult studies, 4 pediatric studies, and 5 with a mixed population of adults and children. Several studies have investigated the kinetics of cTn response after exercise with different biomarkers. The current evidence suggests that sport intensity and duration have significant effects on postexercise cTn elevation, whereas the influence of the type of sport, age, and sex have been not completely defined yet. Most data were obtained during endurance races, whereas evidence is limited (or almost absent), particularly for mixed sports. Data on young adults and professional athletes are limited. Finally, studies on women are extremely limited, and those for non-White are absent. CONCLUSIONS: Postexercise release of cTn can be observed both in young and master athletes and usually represents a physiological phenomenon; however, more rarely, it may unmask a subclinical cardiac disease. The influence of different confounders (age, sex, sport type/intensity/duration, and training level) should be better clarified to establish individualized ranges of normality for postexercise cTn elevation.
Cantinotti et al. (Fri,) conducted a review in Postexercise release of cardiac troponin (n=52). Exercise / Sport was evaluated on Postexercise release of cardiac troponin. Exercise intensity and duration significantly affect postexercise cardiac troponin elevation, which is usually physiological but may rarely unmask subclinical cardiac disease.
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