January 1, 2008Acute Cardiac Care

Early and sustained haemodynamic improvement with levosimendan compared to intraaortic balloon counterpulsation (IABP) in cardiogenic shock complicating acute myocardial infarction

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Why the study?

Does levosimendan improve haemodynamic parameters compared to IABP in patients with cardiogenic shock complicating acute myocardial infarction?

Population

22 patients with intractable cardiogenic shock complicating acute myocardial infarction under standard therapy

Comparison

Levosimendan vs Intra-aortic balloon counterpulsation placement…

Design

Cohort

Follow-up

24 hours

Authors

ACArnd ChristophSankt-Antonius-Hospital Eschweiler RPRoland ProndzinskyHeart Failure & Transplant MRMartin RußHumboldt-Universität zu Berlin

Discussion

Member takes

Implication

May support levosimendan for faster stabilization in post-MI shock; hypothesis-generating and requires RCT confirmation.

Structured PICO

Does levosimendan improve haemodynamic parameters compared to IABP in patients with cardiogenic shock complicating acute myocardial infarction?

Population

22 patients with intractable cardiogenic shock complicating acute myocardial infarction under standard therapy (including PCI, inotropes, and vasopressors)

Intervention

Levosimendan (bolus 12 microg/kg i.v., followed by continuous infusion 0.1 microg/kg/min for 24 h)

Comparator

Intra-aortic balloon counterpulsation (IABP) placement added to standard care

Outcome

Haemodynamic effects including cardiac index (CI), cardiac power index, and systemic vascular resistance (SVR) within 24 hourssurrogate

Levosimendan provides earlier haemodynamic improvement compared to intra-aortic balloon counterpulsation in patients with cardiogenic shock complicating acute myocardial infarction.

Cite This Study

Christoph et al. (2008) studied this question.

synapsesocial.com/papers/6a0faef64fb650da4ffe6437 https://doi.org/10.1080/17482940701358564

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Early and sustained haemodynamic improvement with levosimendan compared to intraaortic balloon counterpulsation (IABP) in cardiogenic shock complicating acute myocardial infarction

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Early and sustained haemodynamic improvement with levosimendan compared to intraaortic balloon counterpulsation (IABP) in cardiogenic shock complicating acute myocardial infarction

Discussion

Member takes

Implication

Structured PICO

Cite This Study

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Also Consider