Why the study?
Does angiographic severity of coronary artery disease predict postoperative death and low cardiac output syndrome in patients undergoing isolated on-pump CABG?
Does angiographic severity of coronary artery disease predict postoperative death and low cardiac output syndrome in patients undergoing isolated on-pump CABG?
Higher angiographic severity of coronary artery disease is associated with an increased risk of immediate postoperative death and low cardiac output syndrome after isolated on-pump CABG.
OBJECTIVE: It is not clear whether the severity of coronary artery disease as assessed on angiography has an impact on the postoperative outcome after coronary artery bypass surgery (CABG). DESIGN: The angiographic status of 15 coronary arteries/segments of 2,233 patients who underwent isolated on-pump CABG was graded according to the following criteria: 1 = no stenosis; 2 = stenosis <50%; 3 = stenosis of 50-69%; 4 = stenosis of 70-89%; 5 = stenosis of 90-99%; 6 = vessel occlusion; and 7 = vessel is not visualized. RESULTS: Thirty-seven patients (1.7%) died during the in-hospital stay and 108 (4.8%) developed postoperatively low cardiac output syndrome. Multivariate analysis showed that along with other risk factors the overall coronary angiographic score was predictive of postoperative death (p = 0.03; OR: 1.027, 95% CI: 1.003-1.052) and of low cardiac output syndrome (p = 0.04; OR: 1.172, 95% CI: 1.010-1.218). The status of the proximal segment of the left circumflex coronary artery, the diagonal arteries and the left obtuse marginal arteries was most closely associated with adverse postoperative outcome. CONCLUSION: The angiographic status of coronary arteries has an impact on the immediate outcome after CABG.
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Biancari et al. (2003) studied this question.
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