Why the study?
To determine whether beta-blockers, aspirin, and statins are underutilized after first-time myocardial infarction in patients with chronic obstructive pulmonary disease compared with those without, and to determine temporal trends and risk factors for non-use.
Does the presence of COPD reduce the utilization of guideline-directed secondary prevention medications (beta-blockers, aspirin, and statins) after first-time myocardial infarction?
Population
140 278 patients hospitalized for first-time MI in Denmark
Comparison
Patients with COPD vs patients without COPD
Design
Nationwide cross-sectional registry-based study
Authors
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COPD-associated non-use of post-MI meds merits clinical attention; leaves open whether targeted interventions improve adherence in comorbid patients.
Does the presence of COPD reduce the utilization of guideline-directed secondary prevention medications (beta-blockers, aspirin, and statins) after first-time myocardial infarction?
Patients with COPD are systematically undertreated with guideline-directed secondary prevention medications following a first-time myocardial infarction, with increasing COPD severity further increasing the risk of non-use.
Rasmussen et al. (2019) studied this question.
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