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November 1, 1992Journal of Biological ChemistryOpen Access

Biochemical pharmacology of (+)- and (-)-2',3'-dideoxy-3'-thiacytidine as anti-hepatitis B virus agents.

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Authors

CCC.N. ChangYale UniversityVSVioletta SkalskiJZJ. H. Zhou

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Chang et al. (1992) studied this question.

synapsesocial.com/papers/6a0fbf48d8c5cf602efd1b93https://doi.org/10.1016/s0021-9258(18)41687-0
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1The separated enantiomers of 2'-deoxy-3'-thiacytidine (BCH 189) both inhibit human immunodeficiency virus replication in vitro1992 · 288 citations
  2. 2Cellular metabolism of 2',3'-dideoxycytidine, a compound active against human immunodeficiency virus in vitro.1987 · 212 citations
  3. 3In Vitro Inhibition of Hepatitis B Virus Replication by 2',3'-Dideoxyguanosine, 2',3'-Dideoxyinosine, and 3'-Azido-2',3'-Dideoxythymidine in 2.2.15 (PR) Cells1991 · 27 citations
  4. 4Common evolutionary origin of hepatitis B virus and retroviruses.1986 · 203 citations
  5. 5Delayed cytotoxicity and selective loss of mitochondrial DNA in cells treated with the anti-human immunodeficiency virus compound 2′,3′-dideoxycytidine1989 · 278 citations