Why the study?
Does adjusted-dose warfarin reduce recurrent stroke compared to aspirin in acute stroke patients with atrial fibrillation?
Population
386 acute stroke patients with atrial fibrillation
Comparison
Adjusted-dose warfarin vs Aspirin in patients with contraindications or…
Design
Cohort
Follow-up
2 years
Authors
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Warfarin was associated with lower cardioembolic recurrence than aspirin after AF stroke; leaves open whether randomized data confirm net benefit.
Does adjusted-dose warfarin reduce recurrent stroke compared to aspirin in acute stroke patients with atrial fibrillation?
Warfarin is superior to aspirin for preventing cardioembolic stroke recurrence in AF patients, but may not offer additional benefit for lacunar stroke recurrence.
Evans et al. (2001) studied this question.
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