Chest pain with unobstructed coronary arteries is a common condition with high morbidity and complex pathophysiology requiring comprehensive management beyond drug therapies.
Supports expanded evaluation beyond angiography; leaves open optimal strategies to reduce high morbidity.
The diagnosis of chest pain with unobstructed coronary arteries is found in one third of patients undergoing investigation of chest pain using coronary angiography. Symptoms are often debilitating and sufferers often have a poor quality of life, with frequent and costly demand on health-care services. Although patients with chest pain and unobstructed coronary arteries do not have increased cardiovascular mortality, morbidity is high. The pathophysiology is complex and management often needs to look beyond drug therapies.
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Webb et al. (2012) studied this question.
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