What question did this study set out to answer?

Review the pathophysiology, clinical manifestations, genetic basis, and prevalence of hypertrophic cardiomyopathy.

Hypertrophic Cardiomyopathy

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Supports heightened clinical vigilance for HCM; leaves open precise prevalence estimates from literature reviews alone.

Review the pathophysiology, clinical manifestations, genetic basis, and prevalence of hypertrophic cardiomyopathy.
Narrative clinical evaluation of hypertrophic cardiomyopathy etiology, epidemiology, and disease manifestations.
Hypertrophic cardiomyopathy is characterized by primary hypertrophy of the left or right ventricle and affects approximately 0.2% of the population (~600,000 Americans).
The disease often stems from autosomal-dominant mutations in sarcomeric protein genes, presenting across a clinical spectrum of dyspnea, angina, presyncope, syncope, and sudden death.

Radhakrishnan Ramaraj (2008) studied this question.

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