Why the study?
Does intracoronary thrombus increase the incidence of ventricular fibrillation compared to coronary ligation in acute regional ischemia in a porcine model?
Does intracoronary thrombus increase the incidence of ventricular fibrillation compared to coronary ligation in acute regional ischemia in a porcine model?
Intracoronary thrombus causes more conduction slowing and increases the risk of ventricular fibrillation compared to coronary ligation in acute regional ischemia, an effect that is abolished by ischemic preconditioning.
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Hypothesis-generating for thrombus as VF trigger in porcine ischemia; leaves open translation to human acute coronary syndromes.
Coronel et al. (1997) studied this question.
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