Population
30 isolated, Langendorff-perfused pig hearts
Comparison
Acute regional ischemia with application of… vs Preocclusion values and nonischemic myocardium
Design
Preclinical
Follow-up
up to 5 minutes of ischemia
Authors
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Wavelength should not guide VF risk assessment in ischemia; leaves open refractory period inhomogeneity as a driver in acute models.
In a porcine model of acute regional ischemia, wavelength is not a useful predictor of ventricular fibrillation due to the rapid development of inhomogeneity in refractoriness.
Opthof et al. (1992) studied this question.
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