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Human papillomavirus (HPV) infections and related diseases are a major problem worldwide. The immune response to human papillomavirus infection in patients with human immunodeficiency virus (HIV) deserves special attention. HPV serves as an etiological agent and biological carcinogen for lesions and cancers associated with HPV. Currently, many possible mechanisms of escape of viruses from factors of innate and adaptive immunity are known. Despite the large amount of accumulated knowledge about the course of HIV and papillomavirus infections, early diagnosis and timely treatment of co-infected patients are difficult, which adversely affects their life prognosis. There is still a need to expand early methods for diagnosing papillomavirus infection in HIV-infected individuals and finding effective treatments.
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Makhorina et al. (2023) studied this question.
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