Key result
HRV shows potential as an autonomic dysfunction biomarker in CVD but requires standardization and validation.
Why the study?
Findings linking reduced heart rate variability to arrhythmias, heart failure, and ischaemic heart disease are mixed, and its prognostic value in cardiovascular disease remains debated.
While HRV shows promise as a biomarker for cardiovascular risk and autonomic dysfunction, significant challenges in standardization and validation remain before it can be widely adopted in clinical practice.
Authors
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HRV monitoring should not yet inform clinical decisions in CVD; leaves open its biomarker role pending standardized prospective validation.
Wang et al. (2026) conducted a review in Cardiovascular disease. Heart rate variability (HRV) assessment and modulation was evaluated. Heart rate variability serves as a potential biomarker for autonomic dysfunction in cardiovascular disease, though its clinical utility requires standardization and validation in larger trials.