Maintaining a better cardiovascular health status for more than 4 years was associated with a 40% lower risk of incident cardiovascular disease events (HR 0.60) compared to 4 years or less.
Cohort (n=83,536)
Does maintaining a better cardiovascular health score for > 4 years reduce the risk of cardiovascular diseases and all-cause mortality in adults?
Maintaining a better cardiovascular health status for more than 6 years is associated with a significantly decreased risk of cardiovascular events and all-cause mortality.
Effect estimate: HR 0.60 (95% CI 0.56-0.63)
BACKGROUND: The protective effect of a higher ideal cardiovascular health (CVH) score on cardiovascular diseases (CVDs) and mortality is well recognized. However, little is known regarding the length of favorable CVH status associated with CVDs and mortality. This study aimed to examined whether the duration of better (ideal or intermediate) CVH is associated with risk of developing CVDs and mortality. METHODS: This prospective cohort study used data from 83,536 individuals from 2006 to 2020 who were enrolled in the Kailuan Study. The CVH scores of individuals were assessed at visits 1, 2, 3, and 4, respectively. The years spent in better CVH were estimated for each individual as the number of examination cycles (0-4) in which the participant was in that CVH score ≥ 8 multiplied by 2 (the mean year interval of each visit). The primary outcomes are CVD events and all-cause mortality. RESULTS: After a median follow-up period of 7.48 years, 5486 (7.07%) cases of incident CVD events and 7669 (9.18%) deaths occurred. Compared with participants in " ≤ 4 years" group, those who maintained for > 4 years had less likely to develop adverse outcomes (CVD events: hazard ratio (HR): 0.60, 95% confidence interval (CI 0.56-0.63; all-cause mortality: HR: 0.77, 95% CI 0.74-0.81). The number of years spent in better CVH was nonlinearly correlated with CVD events or mortality (all Ps for nonlinear < 0.05). The results indicated that maintaining more than 6 years in a better CVH status was associated with a decreased risk of CVD events or mortality. CONCLUSION: Our study indicates that individuals maintaining more than 6 years in better CVH could increase cardiometabolic benefits and a lower risk of all-cause mortality.
Tian et al. (Fri,) conducted a cohort in Cardiovascular diseases and mortality (n=83,536). Maintaining better (ideal or intermediate) cardiovascular health (CVH) for > 4 years vs. Maintaining better CVH for ≤ 4 years was evaluated on Incident CVD events (HR 0.60, 95% CI 0.56-0.63). Maintaining a better cardiovascular health status for more than 4 years was associated with a 40% lower risk of incident cardiovascular disease events (HR 0.60) compared to 4 years or less.