Key result
Glucose intolerance (5.4-11.0 mmol/l) and diabetes (≥11.1 mmol/l) were associated with a significantly increased 10-year risk of mortality from coronary heart disease and stroke.
Why the study?
Does the degree of glycaemia predict 10-year mortality from coronary heart disease and stroke in middle-aged men?
Population
18,403 male civil servants aged 40-64 years
Comparison
Degree of glycaemia vs Normoglycaemia
Design
Cohort
Follow-up
10 years
Authors
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Correlates glucose levels with cardiovascular mortality risk; leaves open whether intervention alters outcomes in middle-aged men.
Cohort (n=18,403)
Does the degree of glycaemia predict 10-year mortality from coronary heart disease and stroke in middle-aged men?
Glucose intolerance and diabetes are significant, independent risk factors for 10-year mortality from coronary heart disease and stroke, highlighting the importance of managing concurrent risk factors like hypertension in these groups.
Fuller et al. (1983) conducted a cohort in Glucose intolerance and diabetes (n=18,403). Degree of glycaemia (glucose intolerance and diabetes) vs. Lower blood glucose values was evaluated on Mortality from coronary heart disease and stroke. Glucose intolerance (5.4-11.0 mmol/l) and diabetes (≥11.1 mmol/l) were associated with a significantly increased 10-year risk of mortality from coronary heart disease and stroke.
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