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May 22, 2026Frontiers in ImmunologyOpen Access

Research landscape, thematic evolution, and translational insights of immune checkpoint inhibitor-induced colitis: a bibliometric analysis (2006-2025)

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Authors

HZHuiyong ZhengCLC LaiFLFangteng Liu

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Overview

Bibliometric analysis reveals trends in immune checkpoint inhibitor-induced colitis, suggesting key future research directions.

Key Points

  • This study analyzes the research landscape and trends in immune checkpoint inhibitor-induced colitis.
  • Systematic literature search in Web of Science Core Collection database
  • Data analysis using CiteSpace and VOSViewer
  • Visualization with Bibliometrix package in R software
  • 1,010 papers identified on ICI-induced colitis covering 62 countries/regions
  • United States led with 470 publications and 41,125 total citations
  • Key research themes include Ipilimumab, immunotherapy, Nivolumab, melanoma, and fecal microbiota transplantation.

Cite This Study

Zheng et al. (2026) studied this question.

synapsesocial.com/papers/6a0ff1dbd674f7c03778b017https://doi.org/10.3389/fimmu.2026.1817557
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  1. 1Mapping the intellectual structure and landscape of colorectal cancer immunotherapy: A bibliometric analysis2024 · 11 citations
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  4. 4Knowledge domains and emerging trends in immune-related adverse events from immune checkpoint inhibitors: A bibliometrics and visualized analysis2024 · 1 citations
  5. 5Immune Checkpoint-Induced Colitis: A Single-Center Retrospective Cohort Study2025