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May 22, 2026Frontiers in PediatricsOpen Access

A prediction nomogram for faltering catch-up growth in full-term small-for-gestational-age infants: a retrospective cohort study

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Authors

QHQian HuSYSufei YangPLPing Li

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Overview

Retrospective cohort study develops a nomogram to predict faltering growth in full-term infants, suggesting early intervention could help.

Key Points

  • This research aims to establish a prediction nomogram for faltering catch-up growth in full-term small-for-gestational-age infants before two years old.
  • Conducted a retrospective cohort study of 1,185 SGA infants from 1996 to 2019 and validated with 294 infants from 2020 to 2023.
  • Defined faltering catch-up growth as failure to increase length-for-age Z score by ≥0.67 by 24 months.
  • Used multivariable logistic regression to identify predictors including sex and Z scores for birth weight, length, and target height.
  • 23.6% of SGA infants in the development cohort experienced faltering catch-up growth.
  • In logistic regression, male sex and lower Z scores for birth weight, length, and target height were significantly associated with faltering growth (all p < 0.05).
  • The nomogram achieved an AUC of 0.784 in the validation cohort, with a sensitivity of 93% and specificity of 56%.

Cite This Study

Hu et al. (2026) studied this question.

synapsesocial.com/papers/6a0ff2a8d674f7c03778b1echttps://doi.org/10.3389/fped.2026.1792285
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