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May 22, 2026European journal of medical researchOpen Access

Factors associated with composite poor outcomes in pediatric osteomyelitis: a systematic review and meta-analysis

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Authors

XJXin JiangQiqihar UniversityTFTong-Tong FengXi'an Honghui HospitalHJHao-Ruo JiaXi'an Honghui Hospital

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Implication

Meta-analysis examines factors influencing poor outcomes in pediatric osteomyelitis, suggesting targeted clinical approaches.

Key Points

  • The analysis aims to identify factors linked to composite poor outcomes in pediatric osteomyelitis to improve early detection and risk stratification.
  • Systematic review of studies involving pediatric patients (ages 0-18) with osteomyelitis.
  • Searched multiple databases and included studies reporting factors associated with poor outcomes.
  • Data analyzed using STATA and study quality assessed with the Newcastle–Ottawa Scale.
  • Delayed source control linked to increased odds of poor outcomes (OR = 2.62, 95% CI 1.63–4.20, P < 0.001).
  • Positive microbial detection significantly associated with poor outcomes (OR = 4.65, 95% CI 2.42–8.95, P < 0.001).
  • MRSA infection showed a strong correlation with poor outcomes (OR = 6.20, 95% CI 3.02–12.73, P < 0.001).

Cite This Study

Jiang et al. (2026) studied this question.

synapsesocial.com/papers/6a0ff2cdd674f7c03778b39ahttps://doi.org/10.1186/s40001-026-04559-7
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Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Subacute Hematogenous Osteomyelitis in Children1982 · 121 citations
  2. 2Imaging tests for the detection of osteomyelitis: a systematic review2019 · 84 citations
  3. 3Changing Trends in Acute Osteomyelitis in Children2008 · 159 citations
  4. 4Early CRP Trends in Childhood Osteomyelitis Predict Complicated Disease2022 · 15 citations