What question did this study set out to answer?

The study aims to develop a multifunctional nanofibrous dressing that enhances chronic wound healing by addressing bacterial infection and inflammation.

May 22, 2026Biomedical Materials

Development and evaluation of a nanofibrous membrane loaded with green-synthesized silver/ andrographolide nanocomposite for infected wound healing

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Authors

JSJiangtao SuHubei University of Technology CLChuchu LiuZhejiang Chinese Medical University YGYu GuoHubei University of Technology

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Implication

Randomized trial shows accelerated wound healing in infected mouse models using a novel nanofibrous dressing, suggesting a new approach for treatment.

Key Points

The study aims to develop a multifunctional nanofibrous dressing that enhances chronic wound healing by addressing bacterial infection and inflammation.
Developed GPA@Ag by electrospinning a gelatin-pullulan membrane with a green-synthesized silver nanocomposite.
Evaluated antibacterial activity against common pathogens and assessed biocompatibility with fibroblast cells.
Conducted wound healing experiments in a Staphylococcus aureus-infected mouse model.
Achieved 97.73% wound closure rate within 14 days in the mouse model.
Demonstrated potent antibacterial activity and high biocompatibility with fibroblast cells.
Promoted collagen deposition and re-epithelialization while effectively reducing inflammation.

Cite This Study

Su et al. (2026) studied this question.

synapsesocial.com/papers/6a0ff2cdd674f7c03778b41b https://doi.org/10.1088/1748-605x/ae7005

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Implication

Randomized trial shows accelerated wound healing in infected mouse models using a novel nanofibrous dressing, suggesting a new approach for treatment.

Development and evaluation of a nanofibrous membrane loaded with green-synthesized silver/ andrographolide nanocomposite for infected wound healing

Discussion

Member takes

Implication

Key Points

Cite This Study

Development and evaluation of a nanofibrous membrane loaded with green-synthesized silver/ andrographolide nanocomposite for infected wound healing

Discussion

Member takes

Implication

Key Points

Cite This Study

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