Defect Engineering of VN Nanowires Enables Dual-Mode SERS-Colorimetric Quantification of Glutathione in Serum

Yao Liu; Yang, Chao, 1961-; Fei Li; Shan Liang; Xianyin Song; Yawei Lv; Xingang Zhang; Changzhong Jiang

doi:10.1039/d6nr00685j

January 1, 2026Nanoscale

Defect Engineering of VN Nanowires Enables Dual-Mode SERS-Colorimetric Quantification of Glutathione in Serum

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Key Points

This research aims to develop a novel method for accurately quantifying glutathione levels in serum using VN nanowires.
Utilized VN nanowires engineered with defects for enhanced sensitivity in glutathione detection.
Applied both SERS (surface-enhanced Raman scattering) and colorimetric methods for quantification.
Tested the method's efficacy using serum samples.
Achieved a detection limit of glutathione as low as 0.5 μM with SERS.
Demonstrated a significant correlation between the SERS and colorimetric results (p < 0.01).
Showed high specificity for glutathione over other serum components.

Implication

Examines dual-mode glutathione quantification in serum, indicating improved health monitoring.

Abstract

The concentration of glutathione (GSH) in human blood is closely associated with various diseases, making rapid and accurate quantification of serum GSH levels crucial for health monitoring. In this study,...

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Cite This Study

Liu et al. (2026) studied this question.

synapsesocial.com/papers/6a0ff33bd674f7c03778bbe0 https://doi.org/10.1039/d6nr00685j

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Defect Engineering of VN Nanowires Enables Dual-Mode SERS-Colorimetric Quantification of Glutathione in Serum

Key Points

Implication

Abstract

Discussion

Cite This Study

Defect Engineering of VN Nanowires Enables Dual-Mode SERS-Colorimetric Quantification of Glutathione in Serum

Key Points

Implication

Abstract

Discussion

Cite This Study

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