Key result
Four-factor nomogram predicts AF recurrence after fluoroscopy-free ablation with a ~0.81 C-index.
Why the study?
This study aimed to identify independent risk factors for AF recurrence after fluoroscopy-free RFA in patients with PAF, and to develop and validate a nomogram model for individualized recurrence risk prediction.
Cohort (n=204)
No
A nomogram incorporating age, left atrial diameter, hypertension, and PAF disease duration provides accurate individualized prediction of AF recurrence risk after zero-fluoroscopy catheter ablation.
This study aimed to identify independent risk factors for atrial fibrillation recurrence after fluoroscopy-free radiofrequency ablation (RFA) in patients with paroxysmal atrial fibrillation (PAF), and to develop and validate a nomogram model for individualized prediction of postprocedural PAF recurrence risk. Clinical data of 204 PAF patients undergoing initial fluoroscopy-free RFA were retrospectively analyzed with a median 18.7-month follow-up, and 20.6% of patients had recurrence.Age, left atrial diameter, hypertension, and PAF disease duration were confirmed as independent recurrence risk factors. The validated nomogram showed excellent predictive performance, with C-indexes of 0.813 and 0.805 in the training and validation sets, respectively. Time-dependent ROC analyses revealed favorable AUC values for 6-month, 1-year and 2-year recurrence prediction. Calibration metrics and sensitivity analysis verified the model’s favorable stability and accuracy.
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Zhao et al. (2026) conducted a cohort in Paroxysmal atrial fibrillation (n=204). Fluoroscopy-free radiofrequency ablation was evaluated on Atrial fibrillation recurrence (sustained AF, atrial flutter, or paroxysmal atrial tachycardia ≥30 seconds after 3-month blanking period). A nomogram incorporating age, left atrial diameter, hypertension, and disease duration accurately predicted atrial fibrillation recurrence after fluoroscopy-free ablation with a C-index of 0.813.
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