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May 22, 2026Chemical Communications

Metal-Free Iodine-Promoted Strategy for the Synthesis of C2,C3-Bissulfenylated Indoles

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Authors

GSGargi SinghMAMariyaraj ArockiarajKMKishor Kumar Mothilal

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Overview

Randomized trial demonstrates an iodine-mediated synthesis of bissulfenylated indoles, suggesting a new synthetic route.

Key Points

  • The aim is to develop a metal-free iodine-mediated approach for synthesizing C2,C3-bissulfenylated indoles from C3 phenylthioindoles.
  • Utilized iodine to mediate the synthesis process
  • Involved C–S bond cleavage of phenylthioindoles
  • Focused on the generation of aromatic groups from the synthesis
  • Successfully synthesized C2,C3-bissulfenylated indoles
  • Achieved efficient C–S bond cleavage in reactions
  • Demonstrated a novel method for indole modification

Cite This Study

Singh et al. (2026) studied this question.

synapsesocial.com/papers/6a0ff3d9d674f7c03778cba2https://doi.org/10.1039/d6cc01055e
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