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February 15, 2006BloodOpen Access

Expression of Jak2V617F causes a polycythemia vera–like disease with associated myelofibrosis in a murine bone marrow transplant model

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GWGerlinde WernigTMThomas MercherRORachel Okabe

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Wernig et al. (2006) studied this question.

synapsesocial.com/papers/6a0ff3fd90ecb39bf65fbb88https://doi.org/10.1182/blood-2005-12-4824
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Also Consider

Synapse has enriched 3 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Discrimination of polycythemias and thrombocytoses by novel, simple, accurate clonality assays and comparison with PRV-1 expression and BFU-E response to erythropoietin2003 · 156 citations
  2. 2The Jak2V617F mutation, PRV-1 overexpression, and EEC formation define a similar cohort of MPD patients2005 · 97 citations
  3. 3Clonal origin and trisomy of chromosome 15 in murine B‐cell malignancies1980 · 25 citations