This comprehensive review analyzes herbal antidiabetic formulations, highlighting their benefits in managing diabetes mellitus.
Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia resulting from defects in insulin secretion, insulin action, or both. Herbal antidiabetic formulations have gained significant importance due to their multi-target mechanisms, safety, and cost-effectiveness. Medicinal plants contain bioactive compounds such as flavonoids, alkaloids, glycosides, terpenoids, and phenolics that exert hypoglycemic effects. These phytoconstituents regulate glucose metabolism through mechanisms including insulin secretion enhancement, inhibition of carbohydrate-digesting enzymes, and improvement of insulin sensitivity. This review discusses medicinal plants, formulation strategies, mechanisms, evaluation parameters, advantages, and future prospects of herbal antidiabetic formulations.
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Khan et al. (2026) studied this question.
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