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January 1, 1990The Journal of Experimental MedicineOpen Access

Cure of murine leishmaniasis with anti-interleukin 4 monoclonal antibody. Evidence for a T cell-dependent, interferon gamma-independent mechanism.

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Authors

MSM D SadickEli Lilly (United States)FHFrederick P. HeinzelSan Francisco General HospitalBHB J HoladayUniversidade Federal do Ceará

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Sadick et al. (1990) studied this question.

synapsesocial.com/papers/6a0ff6fb2badbc352aff0ebbhttps://doi.org/10.1084/jem.171.1.115
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Reciprocal expression of interferon gamma or interleukin 4 during the resolution or progression of murine leishmaniasis. Evidence for expansion of distinct helper T cell subsets.1989 · 1,460 citations
  2. 2Macrophage-activating factor produced by a T cell hybridoma: physiochemical and biosynthetic resemblance to gamma-interferon.1983 · 236 citations
  3. 3Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease1979 · 22,196 citations
  4. 4Cell contact-mediated macrophage activation for antileishmanial defense. II. Identification of effector cell phenotype and genetic restriction.1984 · 28 citations
  5. 5Therapeutic effect of anti-L3T4 monoclonal antibody GK1.5 on cutaneous leishmaniasis in genetically-susceptible BALB/c mice.1985 · 220 citations