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April 1, 1996The American Journal of CardiologyOpen Access

Comparison and reproducibility of visual echocardiographic and quantitative radionyclide left ventricular ejection fractions

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Key result

Equilibrium radionuclide angiography provided more reproducible LVEF measurements than echocardiography, with substantially better limits of agreement (1.8% to 3.6% vs 13.4% to 17.4%).

Why the study?

Does equilibrium radionuclide angiography provide more reproducible LVEF measurements compared to visual estimation by echocardiography in clinically stable patients?

Population

73 clinically stable patients

Comparison

Equilibrium radionuclide angiography for LVEF… vs Visual estimation of LVEF by echocardiography

Design

Cross-sectional, Blinded analysis by 3 echocardiographers and 3 nuclear…

Follow-up

1-week interval for repeat analysis

Authors

NRNiels van RoyenRadboud University NijmegenCJC. Carl JaffeBoston UniversityHKHarlan M. KrumholzYale New Haven Hospital

Discussion

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Implication

May support ERNA for precise LVEF reproducibility in stable patients; leaves open outcome impact before practice change.

Study Design

Type

Observational (n=73)

Blinding

Blinded analysis

Structured PICO

Does equilibrium radionuclide angiography provide more reproducible LVEF measurements compared to visual estimation by echocardiography in clinically stable patients?

P
Population
73 clinically stable patients
I
Intervention
Equilibrium radionuclide angiography for LVEF assessment
C
Comparator
Visual estimation of LVEF by echocardiography
O
Outcome
Comparison of LVEF quantification and reproducibility (intra- and interobserver) between the two methodssurrogate

Main Result

Effect estimate: r = 0.81

Equilibrium radionuclide angiography provides more precisely reproducible LVEF measurements than visual echocardiography, making it preferable when exact reproducibility is required for clinical decisions.

Cite This Study

Royen et al. (1996) conducted an observational in Clinically stable patients (n=73). Equilibrium radionuclide angiography vs. Visual estimation of LVEF by echocardiography was evaluated on Correlation of LVEF determined by both methods (r = 0.81). Equilibrium radionuclide angiography provided more reproducible LVEF measurements than echocardiography, with substantially better limits of agreement (1.8% to 3.6% vs 13.4% to 17.4%).

synapsesocial.com/papers/6a0ffab3d13714ec96feefb3https://doi.org/10.1016/s0002-9149(97)89179-5

Topics

Echocardiography
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Rapid Estimation of Left Ventricular Ejection Fraction in Acute Myocardial Infarction by Echocardiographic Wall Motion Analysis2008 · 123 citations
  2. 2The reproducibility of radionuclide angiographic measurements of left ventricular function in normal subjects at rest and during exercise.1980 · 141 citations
  3. 3Risk Stratification and Survival after Myocardial Infarction1983 · 1,606 citations
  4. 4Effect of Enalapril on Survival in Patients with Reduced Left Ventricular Ejection Fractions and Congestive Heart Failure1991 · 8,072 citations
  5. 5The Effect of Diltiazem on Mortality and Reinfarction after Myocardial Infarction1988 · 827 citations