Why the study?
Does the ratio of right ventricular end-systolic pressure minus left atrial pressure to stroke volume provide a valid assessment of pulmonary arterial load compared to the windkessel model in pigs with pulmonary hypertension?
Does the ratio of right ventricular end-systolic pressure minus left atrial pressure to stroke volume provide a valid assessment of pulmonary arterial load compared to the windkessel model in pigs with pulmonary hypertension?
The ratio of right ventricular end-systolic pressure minus left atrial pressure to stroke volume provides a simple and valid method to assess pulmonary arterial load and its impact on RV function.
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Corrected Ea*(PV) validly estimates pulmonary arterial load in porcine PH models; leaves open translation to clinical RV assessment.
Morimont et al. (2008) studied this question.
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