What question did this study set out to answer?

This review examines the multiple factors leading to hypercholesterolemia and their implications for coronary heart disease prevention.

George Lyman Duff Memorial Lecture. Multifactorial etiology of hypercholesterolemia. Implications for prevention of coronary heart disease.

View Full Paper

Ask AI

Bookmark

Authors

Review explores contributors to hypercholesterolemia in the American public, highlighting prevention strategies for coronary heart disease.

This review examines the multiple factors leading to hypercholesterolemia and their implications for coronary heart disease prevention.
Analysis of dietary factors affecting cholesterol levels in the American population.
Discussion of genetic defects related to hypercholesterolemia and their relationship with dietary sensitivity.
Review of the impact of aging and menopause on LDL receptor activity.
Dietary factors such as cholesterol and saturated fat prominently raise cholesterol levels.
Aging leads to a decline in LDL receptor activity, contributing to borderline-high cholesterol.
Combination therapy is often required for cases of severe hypercholesterolemia due to the coexistence of multiple LDL metabolism defects.

S M Grundy (1991) studied this question.

View Full Paper

Ask AI

Bookmark

Review explores contributors to hypercholesterolemia in the American public, highlighting prevention strategies for coronary heart disease.