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Discussion
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Implication
Meta-analysis reveals high stroke risk linked to hypertension in China, indicating that elevated blood pressure accounts for nearly half of stroke deaths.
Key Points
- To quantify the relationship between hypertension and stroke risk and estimate the population attributable risk of stroke mortality in the People's Republic of China.
- Conducted a systematic meta-analysis by searching MEDLINE and the Chinese Medical Literature Index for epidemiological studies examining hypertension and stroke in China.
- Identified and pooled data from 12 epidemiological studies with N=2,379 stroke cases, combining effect estimates with national census and survey statistics to calculate population attributable risk.
- Hypertension was associated with an overall pooled relative risk of stroke of 5.43 (95% CI, 4.62 to 6.39), with comparable risks observed for hemorrhagic stroke (RR 5.44; 95% CI, 3.99 to 7.40) and ischemic stroke (RR 5.25; 95% CI, 3.95 to 6.98).
- Hypertension accounted for a population attributable risk of 49.5%, corresponding to at least 545,000 excess stroke deaths per year.
Cite This Study
He et al. (1995) studied this question.