Key result
Rare low-grade pharyngeal dedifferentiated liposarcoma presents as a polyp mimicking a benign process.
Why the study?
Dedifferentiated liposarcoma of the upper respiratory tract is an extremely rare occurrence.
Case Report (n=1)
Highlights a rare presentation of dedifferentiated liposarcoma in the upper respiratory tract mimicking a benign polyp.
Rare pharyngeal polyps may harbor dedifferentiated liposarcoma; this case leaves open the need for larger series to refine diagnostic vigilance.
Dedifferentiated liposarcoma is a nonlipogenic sarcoma of variable histological grade that frequently arises in association with a well-differentiated liposarcoma. Dedifferentiation occurs in approximately 10% of well-differentiated liposarcomas and is most commonly encountered in the retroperitoneum. Dedifferentiated liposarcoma of the upper respiratory tract is an extremely rare occurrence. Herein, we report a very rare case of low-grade dedifferentiated liposarcoma of the pharynx that presented as a polyp mimicking a benign process clinically and microscopically. We discuss the relevant molecular findings and review the current literature.
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Georgantzoglou et al. (2021) conducted a case report in Low-grade dedifferentiated liposarcoma of the pharynx (n=1). A rare case of low-grade dedifferentiated liposarcoma of the pharynx presented as a polyp mimicking a benign process clinically and microscopically.
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