Key result
Simple ECGs provide fast early detection of subclinical cardiotoxicity in chemotherapy patients.
Why the study?
ECG provides a fast and accessible tool to detect early signs of subclinical cardiac toxicity during cancer therapy, enabling treatment adjustment before irreversible effects occur.
ECG is a fast and easy tool for the early detection of subclinical cardiac damage in cancer patients, allowing for timely adjustment of chemotherapy to prevent irreversible side effects.
May support ECG monitoring for subclinical cardiotoxicity during chemotherapy; hypothesis-generating and requires prospective validation.
When a cardiologist is asked to evaluate the cardiac toxic effects of chemotherapy, he/she can use several tools: ECG, echocardiography, coronary angiography, ventriculography, and cardiac MRI. Of all these, the fastest and easiest to use is the ECG, which can provide information on the occurrence of cardiac toxic effects and can show early signs of subclinical cardiac damage. These warning signs are the most desired to be recognized by the cardiologist, because the dose of chemotherapeutics can be adjusted so that the clinical side effects do not occur, or the therapy can be stopped in time, before irreversible side effects. This review addresses the problem of early detection of cardiotoxicity in adult and pediatric cancer treatment, by using simple ECG recordings.
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Spînu et al. (2021) conducted a review in Cardiovascular toxicity in cancer treatment. ECG recordings was evaluated. Simple ECG recordings can provide fast and easy early detection of subclinical cardiotoxicity in adult and pediatric cancer patients undergoing chemotherapy.
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