Key result
A novel 720 kD giant protein named obscurin, which binds to titin and contains multiple immunoglobulin-like domains, has been discovered in cross-striated muscle cells.
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Obscurin discovery extends sarcomeric protein mapping in striated muscle; leaves open its roles in cardiac function and disease.
Sanger et al. (2001) studied this question. A novel 720 kD giant protein named obscurin, which binds to titin and contains multiple immunoglobulin-like domains, has been discovered in cross-striated muscle cells.
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