Why the study?
The effect of initiating statins for secondary prevention after a first MI in patients aged 80 years and older required exploration.
Does initiating statins for at least 2 years reduce the composite of recurrent MI, stroke, and cardiovascular mortality in patients aged 80 years and older after a first MI?
Population
9020 patients aged 65 years and older hospitalized after a first MI
Comparison
At least 2 years of statin prescription vs untreated and less than 2 years
Design
Retrospective cohort study
Follow-up
Median 4.5 years
Authors
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Statin use for 2 years was associated with lower risk post-MI in patients ≥80; leaves open confirmation in randomized trials.
Does initiating statins for at least 2 years reduce the composite of recurrent MI, stroke, and cardiovascular mortality in patients aged 80 years and older after a first MI?
Initiating statins for secondary prevention after a first MI in patients aged 80 years and older reduces cardiovascular events and mortality if continued for at least 2 years.
Lefeber et al. (2019) studied this question.
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